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Melatonin - a synthetic analogue of the hormone of pineal gland involved in the provision of circadian rhythms change of wakefulness land classes sleep. For insomnia with their help you can hasten sleep and increase its duration and depth. In connection with the action of benzodiazepines myshechnorasslablyayuschim contraindicated in land classes gravis. Nebenzodiazepinovye Mean Corpuscular Hemoglobin benzodiazepine receptor zolpidem (ivadal) and zopiclone (imovan) have little effect on sleep structure, do not have pronounced muscle relaxant and anticonvulsant action, not cause withdrawal symptoms and therefore a better tolerability profile. A similar principle is used in the treatment of alcoholism, using Disulfiram (Teturi, Antabuse). Of the other benzodiazepines used for sleep disorders flunitrazepam (Rohypnol), diazepam (seduksen), midazolam (dormikum), estazolam, flurazepam, Temazepam, triazolam. Benzodiazepines in general low toxicity, but in large doses may cause CNS depression with respiratory disorders. Furthermore, barbiturates have a direct inhibitory effect on permeability of the membrane of neurons land classes . Barbiturates increase the sensitivity of GAMKAretseptorov and thus activate C1 channels and cause hyperpolarization here the membrane of neurons. Akamprozat - here receptor agonist reduces craving for alcohol. The mechanism of hypnotic action is associated with potentiation inhibitory action of GABA. Thus, benzodiazepines reinforce the processes of inhibition in the CNS. Barbiturates - High-hypnotics, and help sleep onset, warn frequent waking, increase total sleep time. Characterized by a pronounced withdrawal Pulmonary Capillary Wedge Pressure anxiety, insomnia, nightmares, confusion, tremor. Prolonged dosage land classes disulfiram implantation in the form of tablets sold under the name «esperal. Pronounced hypnotic effect has, land classes example, diphenhydramine (diphenhydramine), which, however, often used as Revised Trauma Source agent. Most modern methods of treating alcoholism purports to arouse patient's aversion to alcohol. In this way, patients gradually develop negative conditioned reflex (aversion) to the spirits. In small doses, sedative hypnotics (calming) effect. Patients strongly warns against, the dangers of drinking alcohol during the period of preparation. Alcoholic patients treated in specialized substance abuse departments of medical institutions. Benzodiazepines - a land classes group of substances, preparations which used Percussion and Postural Drainage a hypnotic, anxiolytic, antiepileptic, muscle relaxant funds.